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The death of a young French sailor on August 3, 1793 marked the beginning of a crippling epidemic that took hold of Philadelphia, then the nation’s capital, and threatened the stability of a fledgling country, leaving between 4,000 and 5,000 dead. Using medical and non-medical accounts to recreate the fear that took hold of the city, the author spotlights those who were forced to flee, President Washington among them, and the heroic residents who stayed to help combat the spread of the disease. An American Plague brings together science, history, politics, and public health to tell the story of a nation in crisis.